The ACSL4 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ACSL3, ACSL4, and FACL4. This antibody recognizes Human antigen. The ACSL4 Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants